MALARIA ANTIGEN

ELISA Malaria Antigen kit

Malaria Antigen ELISA (REF. 650101 / REF. 650105)

The apDia Malaria Antigen ELISA is an in vitro diagnostic immunoassay (IVD) for the qualitative determination of Plasmodium spp LDH in blood samples. The apDia Malaria antigen test can be used for the detection of the malarial antigen pLDH of any of the four species in blood samples. It may also be used for culture samples to measure in vitro drug susceptibility.

Malaria is a serious, sometimes fatal blood-born parasitic disease resulting from infection with protozoa of the genus Plasmodium and is transmitted by the bite of Anopheles mosquitoes. About half of the world’s population is at risk of malaria, leading to 250 million malaria cases yearly and nearly one million deaths. Four species infect humans: P. falciparum, P. vivax, P. ovale and P. malariae.

Prompt and accurate diagnosis of malaria is needed for implementation of appropriate treatment to reduce associated morbidity and mortality. The first symptoms (most often fever, chills, sweats, headaches, muscle pains, nausea and vomiting) are not specific and may resemble those of many other infectious diseases like the flu. In severe malaria, clinical findings (confusion, coma, neurologic focal signs, severe anemia, respiratory difficulties) are more striking and may increase the suspicion index for malaria. It is essential to confirm the clinical diagnosis with results from the laboratory. Treatment must start early to cure the disease effectively and is also important in preventing the spreading of the disease.

Laboratory diagnosis of malaria is based on the identification of the malaria parasite or its antigens in the blood of the patient. While microscopy is considered as the gold standard, assays detecting the Plasmodium specific enzyme lactate dehydrogenase (pLDH) are considered a prominent alternative. All four human malarial parasites produce a unique pLDH activity and its presence follows the level of parasitemia making it a good monitoring tool for following active malarial infections. Even though malaria is a tropical disease, cases of malaria may appear all over the world due to increased travelling practices. As the disease may also be transmitted by blood transfusion, control of donor blood for the presence of the parasite is essential.

WHY CHOOSE FOR

MALARIA ANTIGEN 2x 96 TESTS, REF. 650101
MALARIA ANTIGEN 5x 96 TESTS, REF. 650105

The ELISA kits offered by apDia are validated on open ELISA automates such as the Dynex Instruments.

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