hsCRP ELISA (REF. 740011)

Enzyme Immunoassay for the Quantitative High Sensitive Determination of C-Reactive Protein in Human Serum and Plasma.

C-Reactive Protein (CRP) is an acute-phase protein, produced exclusively in the liver. Interleukin-6 is the mediator for the synthesis by the hepatocytes of CRP, a pentamer of approximately 120.000 Daltons. CRP is present in the serum of normal persons at concentrations ranging up to 5 mg/l.

A series of prospective studies provide consistent data documenting that mild elevation of baseline levels of CRP among apparently healthy individuals is associated with higher long-term risk for future cardiovascular events. This predictive capacity of CRP is independent of traditional cardiovascular risk factors and offers a prognostic advantage over measurement of lipid alone. Inflammatory markers specifically hsCRP may help to identify those who would benefit most from these pharmacological intervention. hsCRP is the novel and evolving biomarker which provides a most useful predictive indicator for subsequent cardiovascular events.

This test should not be used for assessment of acute inflammation but should be ordered to evaluate CVD (Cardiovascular Disease) risk in apparently healthy individuals who have not had recent infection or other serious illness. For the assessment of acute inflammation the CRP ELISA ref 740001 from apDia can be used.


hsCRP KIT 96 TESTS, REF. 740011

The ELISA kits offered by apDia are validated on open ELISA automates such as the Dynex Instruments.



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